Research workbench
Crystal structures and thermostability of mutant TRAP3 A5 (engineered trap)
Analyse Crystal structures and thermostability of mutant TRAP3 A5 (engineered trap) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2ZD0
- Type
- protein
- Length
- 195 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcription attenuation protein mtrb
- UniProt
- Q9X6J6
- Ligands
- TRP
- Pockets
- 3 · best druggability 0.74
Structure
x-ray diffraction · 2 distinct chains · 0% helix, 61% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcription attenuation protein mtrb | protein | 63 | 0% helix, 60% strand | Q9X6J6 |
| B, C | Transcription attenuation protein mtrb | protein | 66 | 0% helix, 62% strand | Q9X6J6 |
Ligands and binding sites
- TRP · Tryptophan · ligand · 3 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 82 | 0.74 | 0.97 | 21 | TRP |
| 2 | 88 | 0.74 | 0.97 | 18 | TRP |
| 3 | 76 | 0.42 | 0.79 | 17 | empty |
Interfaces
2 interfaces between chains.
- B–C · 1033 Ų buried · 18 hydrogen bonds · protein-protein
- A–B · 913 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 2ZD0 · Crystal structures and thermostability of mutant TRAP3 A5 (ENGINEERED TRAP) · the same entry in another collection · chain A against A, TM-score 1.00
- Q9X6J6 · AlphaFold monomer V2.0 prediction for transcription attenuation protein mtrb (Q9X6J6) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X6J6
- Elsewhere: RCSB PDB 2ZD0 · PDBe 2ZD0 · UniProt Q9X6J6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.