Research workbench
Crystal structure of uncharacterized conserved protein from thermotoga maritima
Analyse Crystal structure of uncharacterized conserved protein from thermotoga maritima in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2YZO
- Type
- protein
- Length
- 447 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable 2-phosphosulfolactate phosphatase
- EC
- 3.1.3.71
- UniProt
- Q9WZQ4
- Ligands
- MLT
- Pockets
- 2 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 39% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable 2-phosphosulfolactate phosphatase (EC 3.1.3.71) | protein | 223 | 39% helix, 22% strand | Q9WZQ4 |
| B | Probable 2-phosphosulfolactate phosphatase (EC 3.1.3.71) | protein | 224 | 39% helix, 23% strand | Q9WZQ4 |
Ligands and binding sites
- MLT · D-malate · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 265 | 0.71 | 0.86 | 50 | MLT |
| 2 | 167 | 0.65 | 0.86 | 39 | MLT |
Interfaces
1 interface between chains.
- A–B · 1152 Ų buried · 19 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 2YZO · Crystal structure of uncharacterized conserved protein from Thermotoga maritima · the same entry in another collection · chain A against A, TM-score 1.00
- Q9WZQ4 · AlphaFold monomer V2.0 prediction for probable 2-phosphosulfolactate phosphatase (Q9WZQ4) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WZQ4
- Elsewhere: RCSB PDB 2YZO · PDBe 2YZO · UniProt Q9WZQ4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.