Research workbench
Crystal structure of PF12 tandem 6-cys domains from plasmodium falciparum
Analyse Crystal structure of PF12 tandem 6-cys domains from plasmodium falciparum in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2YMO
- Type
- protein
- Length
- 221 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PF12
- UniProt
- C6KSX0
- Pockets
- 2 · best druggability 0.28
Structure
x-ray diffraction · 1 distinct chain · 2% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | PF12 | protein | 221 | 2% helix, 44% strand | C6KSX0 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.28 | 0.75 | 10 | empty |
| 2 | 61 | 0.28 | 0.73 | 12 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 2YMO · Crystal structure of Pf12 tandem 6-cys domains from Plasmodium falciparum · the same entry in another collection · chain A against A, TM-score 1.00
- C6KSX0 · AlphaFold monomer V2.0 prediction for merozoite surface protein P12 (C6KSX0) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C6KSX0
- Elsewhere: RCSB PDB 2YMO · PDBe 2YMO · UniProt C6KSX0
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