Research workbench
Crystal structure of P110BETA in complex with ICSH2 of P85BETA and the drug gdc-0941
Analyse Crystal structure of P110BETA in complex with ICSH2 of P85BETA and the drug… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2Y3A
- Type
- protein
- Length
- 1,212 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8BTI9, O08908
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 976 | — | Q8BTI9 |
| B | — | protein | 236 | — | O08908 |
Compared structures
- 2Y3A · Crystal structure of p110beta in complex with icSH2 of p85beta and the drug GDC-0941 · the same entry in another collection · chain A against A, TM-score 1.00
- Q8BTI9 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 4,5-bisphosphate 3-kinase… · a predicted model of the same protein · chain A against A, TM-score 0.96
- O08908 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 3-kinase regulatory subunit… · a predicted model of the same protein · chain B against A, TM-score 0.72
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8BTI9
- Every structure of UniProt O08908
- Elsewhere: RCSB PDB 2Y3A · PDBe 2Y3A · UniProt Q8BTI9 · UniProt O08908
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