Research workbench
Reassembly and co-crystallization of a family 9 processive endoglucanase from separately expressed GH9 and CBM3C modules
Analyse Reassembly and co-crystallization of a family 9 processive endoglucanase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2XFG
- Type
- protein
- Length
- 618 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Endoglucanase 1
- EC
- 3.2.1.4
- UniProt
- Q02934
- Ligands
- CA, CL
- Pockets
- 2 · best druggability 0.56
Structure
x-ray diffraction · 2 distinct chains · 37% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endoglucanase 1 (EC 3.2.1.4) | protein | 446 | 48% helix, 7% strand | Q02934 |
| B | Endoglucanase 1 | protein | 172 | 8% helix, 39% strand | Q02934 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 244 | 0.56 | 0.78 | 30 | empty |
| 2 | 126 | 0.40 | 0.75 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 1136 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
- 2XFG · Reassembly and co-crystallization of a family 9 processive endoglucanase from separately… · the same entry in another collection · chain A against A, TM-score 1.00
- Q02934 · AlphaFold monomer V2.0 prediction for endoglucanase 1 (Q02934) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02934
- Elsewhere: RCSB PDB 2XFG · PDBe 2XFG · UniProt Q02934
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