Research workbench
Tailspike protein of E. COLI bacteriophage HK620 in complex with hexasaccharide
Analyse Tailspike protein of E. COLI bacteriophage HK620 in complex with hexasaccharide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2X85
- Type
- protein
- Length
- 597 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tailspike protein HK620
- UniProt
- Q9AYY6
- Ligands
- NAG, GLC, GLA, RAM, NA
- Pockets
- 3 · best druggability 0.49
Structure
x-ray diffraction · 1 distinct chain · 9% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tailspike protein HK620 | protein | 597 | 9% helix, 43% strand | Q9AYY6 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
- GLC · alpha-D-glucopyranose · sugar · 2 copies · chains A
- GLA · alpha-D-galactopyranose · sugar · chains A
- RAM · alpha-L-rhamnopyranose · sugar · chains A
- NA · Sodium ion · metal · 4 copies · chains A
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 153 | 0.49 | 0.78 | 25 | NAG, GLC, NA |
| 2 | 118 | 0.44 | 0.77 | 18 | RAM, NAG |
| 3 | 96 | 0.35 | 0.74 | 19 | empty |
Compared structures
- 2X85 · Tailspike protein of E. coli bacteriophage HK620 in complex with hexasaccharide · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9AYY6
- Elsewhere: RCSB PDB 2X85 · PDBe 2X85 · UniProt Q9AYY6
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