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The conserved candida albicans CA3427 gene product defines a new family of proteins exhibiting the generic periplasmic binding protein structural fold

Analyse The conserved candida albicans CA3427 gene product defines a new family of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2X7Q
Type: protein
Length: 306 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Possible thiamine biosynthesis enzyme
UniProt: Q59X88
Ligands: CA
Pockets: 1 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Possible thiamine biosynthesis enzyme	protein	306	45% helix, 20% strand	Q59X88

Ligands and binding sites

CA · Calcium ion · metal · 2 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	252	0.64	0.81	41	empty

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

2X7Q · The conserved Candida albicans CA3427 gene product defines a new family of proteins… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q59X88
Elsewhere: RCSB PDB 2X7Q · PDBe 2X7Q · UniProt Q59X88

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