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Structure of a single domain camelid antibody fragment in complex with a C-terminal peptide of alpha-synuclein

Analyse Structure of a single domain camelid antibody fragment in complex with a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2X6M
Type
protein
Length
132 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Heavy chain variable domain from dromedary; Alpha-synuclein peptide
UniProt
P37840

Structure

x-ray diffraction · 2 distinct chains · 9% helix, 47% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AHeavy chain variable domain from dromedaryprotein12610% helix, 49% strand—
BAlpha-synuclein peptideprotein60% helix, 0% strandP37840

Interfaces

1 interface between chains.

  • A–B · 333 Ų buried · 11 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

  • 2X6M · Structure of a single domain camelid antibody fragment in complex with a C-terminal… · the same entry in another collection · chain A against A, TM-score 1.00

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