Research workbench
Semi-synthetic analogue of human insulin NMEALAB26-insulin at pH 7.5
Analyse Semi-synthetic analogue of human insulin NMEALAB26-insulin at pH 7.5 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2WS0
- Type
- protein
- Length
- 48 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Insulin a chain; Insulin B chain
- UniProt
- P01308
Structure
x-ray diffraction · 2 distinct chains · 56% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Insulin a chain | protein | 21 | 57% helix, 0% strand | P01308 |
| B | Insulin B chain | protein | 27 | 56% helix, 0% strand | P01308 |
Interfaces
1 interface between chains.
- A–B · 512 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 3 disulfide, 1 modified (disulfide, nonstandard).
Compared structures
- 2WS0 · Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5 · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01308
- Elsewhere: RCSB PDB 2WS0 · PDBe 2WS0 · UniProt P01308
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