Research workbench
The 1.7 a crystal structure of a bleomycin resistance determinant encoded on the transposon TN5
Analyse The 1.7 a crystal structure of a bleomycin resistance determinant encoded on… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1ECS
- Type
- protein
- Length
- 240 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Bleomycin resistance protein
- UniProt
- P13081
- Ligands
- CA
- Pockets
- 5 · best druggability 0.40
Structure
x-ray diffraction · 1 distinct chain · 18% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Bleomycin resistance protein | protein | 120 | 18% helix, 43% strand | P13081 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 108 | 0.40 | 0.75 | 18 | PG4 |
| 2 | 100 | 0.38 | 0.75 | 17 | PG4 |
| 3 | 82 | 0.34 | 0.75 | 16 | empty |
| 4 | 59 | 0.27 | 0.73 | 17 | empty |
| 5 | 62 | 0.25 | 0.71 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 1319 Ų buried · 28 hydrogen bonds · protein-protein
Compared structures
- 1ECS · The 1.7 a crystal structure of a bleomycin resistance determinant encoded on the… · the same entry in another collection · chain A against A, TM-score 1.00
- P13081 · AlphaFold monomer V2.0 prediction for bleomycin resistance protein (P13081) · a predicted model of the same protein · chain B against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13081
- Elsewhere: RCSB PDB 1ECS · PDBe 1ECS · UniProt P13081
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