Research workbench
Saccharomyces cerevisiae GAS2P in complex with laminaritriose and laminaritetraose
Analyse Saccharomyces cerevisiae GAS2P in complex with laminaritriose and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2W63
- Type
- protein
- Length
- 432 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycolipid-anchored surface protein 2
- EC
- 2.4.1.-
- UniProt
- Q06135
- Ligands
- BGC
- Pockets
- 3 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycolipid-anchored surface protein 2 (EC 2.4.1.-) | protein | 432 | 34% helix, 17% strand | Q06135 |
Ligands and binding sites
- BGC · beta-D-glucopyranose · sugar · 7 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 223 | 0.51 | 0.75 | 32 | empty |
| 2 | 138 | 0.43 | 0.76 | 25 | BGC |
| 3 | 54 | 0.24 | 0.71 | 15 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 2W63 · Saccharomyces cerevisiae GAS2P in complex with laminaritriose and laminaritetraose · the same entry in another collection · chain A against A, TM-score 1.00
- Q06135 · AlphaFold monomer V2.0 prediction for 1,3-beta-glucanosyltransferase GAS2 (Q06135) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q06135
- Elsewhere: RCSB PDB 2W63 · PDBe 2W63 · UniProt Q06135
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