Research workbench
Glucosamine-6-phosphate synthase in complex with glucosamine-6- phosphate
Analyse Glucosamine-6-phosphate synthase in complex with glucosamine-6- phosphate in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2VF5
- Type
- protein
- Length
- 366 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glucosamine--fructose-6-phosphate aminotransferase
- EC
- 2.6.1.16
- UniProt
- P17169
- Ligands
- GLP
- Pockets
- 2 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | Glucosamine--fructose-6-phosphate aminotransferase (EC 2.6.1.16) | protein | 366 | 46% helix, 14% strand | P17169 |
Ligands and binding sites
- GLP · 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose · ligand · chains X
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 176 | 0.58 | 0.82 | 26 | GLP |
| 2 | 145 | 0.44 | 0.76 | 24 | empty |
Compared structures
- 2VF5 · Glucosamine-6-phosphate synthase in complex with glucosamine-6- phosphate · the same entry in another collection · chain X against X, TM-score 1.00
- P17169 · AlphaFold monomer V2.0 prediction for glutamine--fructose-6-phosphate aminotransferase… · a predicted model of the same protein · chain X against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17169
- Elsewhere: RCSB PDB 2VF5 · PDBe 2VF5 · UniProt P17169
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