UniProt P17169
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (P17169)
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (UniProt P17169), EC 2.6.1.16: 22 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and experiment…
- UniProt
- P17169
- Protein
- Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
- EC
- 2.6.1.16
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
23 records of P17169 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JXA | Glucosamine 6-phosphate synthase with glucose 6-phosphate | x-ray diffraction | A, B, C | — | — |
| 1JXA | Glucosamine 6-phosphate synthase with glucose 6-phosphate | x-ray diffraction | A, B, C | — | — |
| 1MOQ | Isomerase domain of glucosamine 6-phosphate synthase complexed with glucosamine 6-phosphate | x-ray diffraction | A | — | — |
| 1MOQ | Isomerase domain of glucosamine 6-phosphate synthase complexed with glucosamine 6-phosphate | x-ray diffraction | A | — | — |
| 1MOR | Isomerase domain of glucosamine 6-phosphate synthase complexed with glucose 6-phosphate | x-ray diffraction | A | — | — |
| 1MOR | Isomerase domain of glucosamine 6-phosphate synthase complexed with glucose 6-phosphate | x-ray diffraction | A | — | — |
| 1MOS | Isomerase domain of glucosamine 6-phosphate synthase complexed with 2-amino-2-deoxyglucitol… | x-ray diffraction | A | — | — |
| 1MOS | Isomerase domain of glucosamine 6-phosphate synthase complexed with 2- amino-2-deoxyglucitol… | x-ray diffraction | A | — | — |
| 1XFF | Glutaminase domain of glucosamine 6-phosphate synthase complexed with glutamate | x-ray diffraction | A, B | — | — |
| 1XFF | Glutaminase domain of glucosamine 6-phosphate synthase complexed with glutamate | x-ray diffraction | A, B | — | — |
| 1XFG | Glutaminase domain of glucosamine 6-phosphate synthase complexed with l-glu hydroxamate | x-ray diffraction | A, B | — | — |
| 1XFG | Glutaminase domain of glucosamine 6-phosphate synthase complexed with L-glu hydroxamate | x-ray diffraction | A, B | — | — |
| 2J6H | E. coli glucosamine-6-P synthase in complex with glucose-6P and 5-oxo- L-norleucine | x-ray diffraction | A, B | — | — |
| 2J6H | E. COLI glucosamine-6-P synthase in complex with glucose-6P and 5-oxo-L-norleucine | x-ray diffraction | A, B | — | — |
| 2VF4 | E. coli glucosamine-6-P synthase | x-ray diffraction | X | — | — |
| 2VF4 | E. COLI glucosamine-6-P synthase | x-ray diffraction | X | — | — |
| 2VF5 | Glucosamine-6-phosphate synthase in complex with glucosamine-6- phosphate | x-ray diffraction | X | — | — |
| 2VF5 | Glucosamine-6-phosphate synthase in complex with glucosamine-6- phosphate | x-ray diffraction | X | — | — |
| 4AMV | E.COLI glucosamine-6P synthase in complex with fructose-6P | x-ray diffraction | A, B, C | — | — |
| 4AMV | E.COLI glucosamine-6P synthase in complex with fructose-6P | x-ray diffraction | A, B, C | — | — |
| 7DNR | Crystal Structure of Zn-bound SIS Domain of Glucosamine-6-P Synthase from E. coli | x-ray diffraction | A, B | ZN | 6 (best 0.88) |
| 7DNR | Crystal structure of zn-bound sis domain of glucosamine-6-P synthase from E. COLI | x-ray diffraction | A, B | ZN | — |
| P17169 | AlphaFold monomer V2.0 prediction for glutamine--fructose-6-phosphate aminotransferase… | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 1XFG chain B against the predicted model P17169: TM-score 0.99, RMSD 0.79 Å
- 1XFG chain B against the predicted model P17169: TM-score 0.99, RMSD 0.79 Å
- 1XFF chain A against the predicted model P17169: TM-score 0.99, RMSD 0.80 Å
- 1XFF chain A against the predicted model P17169: TM-score 0.99, RMSD 0.80 Å
- 1XFG chain A against the predicted model P17169: TM-score 0.99, RMSD 0.80 Å
- 1XFG chain A against the predicted model P17169: TM-score 0.99, RMSD 0.80 Å
- 1XFF chain B against the predicted model P17169: TM-score 0.99, RMSD 0.90 Å
- 1XFF chain B against the predicted model P17169: TM-score 0.99, RMSD 0.90 Å
- 7DNR chain B against the predicted model P17169: TM-score 0.99, RMSD 0.83 Å
- 7DNR chain B against the predicted model P17169: TM-score 0.99, RMSD 0.83 Å
Elsewhere
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