Structural model for the complex between the dr adhesins and carcinoembryonic antigen (cea)

Structure

solution nmr · 2 distinct chains · 2% helix, 49% strand (DSSP).

Ligands and binding sites

• MTN · S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate · ligand · 3 copies · chains A, N

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–N · 721 Ų buried · 14 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 covalent, 1 disulfide (covalent ligand, disulfide).

Compared structures

• 2VER · Structural model for the complex between the Dr adhesins and carcinoembryonic antigen… · the same entry in another collection · chain A against A, TM-score 1.00
• P06731 · AlphaFold monomer V2.0 prediction for carcinoembryonic antigen- related cell adhesion… · a predicted model of the same protein · chain N against A, TM-score 0.96
• Q57254 · AlphaFold monomer V2.0 prediction for afimbrial adhesin afa-III (Q57254) · a predicted model of the same protein · chain A against A, TM-score 0.66

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q57254
• Every structure of UniProt P06731
• Elsewhere: RCSB PDB 2VER · PDBe 2VER · UniProt Q57254 · UniProt P06731