UniProt P06731
Carcinoembryonic antigen-related cell adhesion molecule 5 (P06731)
Carcinoembryonic antigen-related cell adhesion molecule 5 (UniProt P06731): 9 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P06731
- Protein
- Carcinoembryonic antigen-related cell adhesion molecule 5
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 0 records with a druggable one
Structures
10 records of P06731 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1E07 | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental… | solution scattering | A | — | — |
| 1E07 | Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental… | solution scattering | A | — | — |
| 2QSQ | Crystal structure of the N-terminal domain of carcinoembryonic antigen (CEA) | x-ray diffraction | A, B | — | — |
| 2QSQ | Crystal structure of the N-terminal domain of carcinoembryonic antigen (cea) | x-ray diffraction | A, B | — | — |
| 2QST | Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA) | x-ray diffraction | A, B | — | — |
| 2QST | Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (cea) | x-ray diffraction | A, B | — | — |
| 2VER | Structural model for the complex between the Dr adhesins and carcinoembryonic antigen (CEA) | solution nmr | N | — | — |
| 2VER | Structural model for the complex between the dr adhesins and carcinoembryonic antigen (cea) | solution nmr | N | — | — |
| 8BW0 | Structure of CEACAM5 A3-B3 domain in Complex with Tusamitamab Fab | electron microscopy | C | NAG, FUC | 3 (best 0.31) |
| P06731 | AlphaFold monomer V2.0 prediction for carcinoembryonic antigen- related cell adhesion molecule 5… | predicted | A | — | — |
Ligands
Experiment against prediction
- 2QST chain A against the predicted model P06731: TM-score 0.97, RMSD 0.65 Å
- 2QST chain A against the predicted model P06731: TM-score 0.97, RMSD 0.65 Å
- 2QSQ chain B against the predicted model P06731: TM-score 0.97, RMSD 0.74 Å
- 2QSQ chain B against the predicted model P06731: TM-score 0.97, RMSD 0.74 Å
- 2QSQ chain A against the predicted model P06731: TM-score 0.97, RMSD 0.71 Å
- 2QSQ chain A against the predicted model P06731: TM-score 0.97, RMSD 0.71 Å
- 2VER chain N against the predicted model P06731: TM-score 0.96, RMSD 0.81 Å
- 2VER chain N against the predicted model P06731: TM-score 0.96, RMSD 0.81 Å
- 8BW0 chain C against the predicted model P06731: TM-score 0.94, RMSD 1.31 Å
- 2QST chain B against the predicted model P06731: TM-score 0.94, RMSD 1.34 Å
Elsewhere
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