Research workbench
The structure of the family 40 cbm from C. perfringens nanj in complex with a sialic acid containing molecule
Analyse The structure of the family 40 cbm from C. perfringens nanj in complex with a… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2V73
- Type
- protein
- Length
- 365 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative exo-alpha-sialidase
- UniProt
- Q0TTQ4
- Ligands
- SIA, CA
- Pockets
- 1 · best druggability 0.43
Structure
x-ray diffraction · 2 distinct chains · 12% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative exo-alpha-sialidase | protein | 183 | 13% helix, 45% strand | Q0TTQ4 |
| B | Putative exo-alpha-sialidase | protein | 182 | 12% helix, 43% strand | Q0TTQ4 |
Ligands and binding sites
- SIA · N-acetyl-alpha-neuraminic acid · sugar · chains A
- CA · Calcium ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 203 | 0.43 | 0.73 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 47 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 2V73 · The structure of the family 40 CBM from C. perfringens NanJ in complex with a sialic acid… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0TTQ4
- Elsewhere: RCSB PDB 2V73 · PDBe 2V73 · UniProt Q0TTQ4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.