Stractural insight into the interaction between escrt-III and VPS4

Structure

x-ray diffraction · 2 distinct chains · 71% helix, 0% strand (DSSP).

Ligands and binding sites

• SO4 · Sulfate ion · ion · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 1353 Ų buried · 20 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

• 2V6X · Stractural insight into the interaction between ESCRT-III and Vps4 · the same entry in another collection · chain A against A, TM-score 1.00
• P52917 · AlphaFold monomer V2.0 prediction for vacuolar protein sorting- associated protein 4… · a predicted model of the same protein · chain A against A, TM-score 0.91
• P36108 · AlphaFold monomer V2.0 prediction for DOA4-independent degradation protein 4 (P36108) · a predicted model of the same protein · chain B against A, TM-score 0.33

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P52917
• Every structure of UniProt P36108
• Elsewhere: RCSB PDB 2V6X · PDBe 2V6X · UniProt P52917 · UniProt P36108