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Human mir-receptor, repeat 11

Analyse Human mir-receptor, repeat 11 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1E6F
Type: protein
Length: 260 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cation-independent mannose-6-phosphate receptor
UniProt: P11717
Pockets: 2 · best druggability 0.36

Structure

x-ray diffraction · 2 distinct chains · 5% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cation-independent mannose-6-phosphate receptor	protein	129	5% helix, 44% strand	P11717
B	Cation-independent mannose-6-phosphate receptor	protein	131	5% helix, 42% strand	P11717

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	62	0.36	0.78	20	empty
2	67	0.31	0.75	19	empty

Interfaces

1 interface between chains.

A–B · 373 Å² buried · 7 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 disulfide (disulfide).

Compared structures

1E6F · Human MIR-receptor, repeat 11 · the same entry in another collection · chain A against A, TM-score 1.00
P11717 · AlphaFold monomer V2.0 prediction for cation-independent mannose-6-phosphate receptor… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P11717
Elsewhere: RCSB PDB 1E6F · PDBe 1E6F · UniProt P11717

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