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High resolution DHFR R-67

Analyse High resolution DHFR R-67 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2RH2
Type: protein
Length: 57 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dihydrofolate reductase type 2
EC: 1.5.1.3
UniProt: P00383

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dihydrofolate reductase type 2 (EC 1.5.1.3)	protein	57	5% helix, 46% strand	P00383

Ligands and binding sites

MRD · (4R)-2-methylpentane-2,4-diol · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

2RH2 · High Resolution DHFR R-67 · the same entry in another collection · chain A against A, TM-score 1.00
P00383 · AlphaFold monomer V2.0 prediction for dihydrofolate reductase type 2 (P00383) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00383
Elsewhere: RCSB PDB 2RH2 · PDBe 2RH2 · UniProt P00383

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