Research workbench
Ribonucleotide reductase R2F protein from salmonella typhimurium (oxidized)
Analyse Ribonucleotide reductase R2F protein from salmonella typhimurium (oxidized) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2R2F
- Type
- protein
- Length
- 571 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein (ribonucleoside-diphosphate reductase small chain)
- EC
- 1.17.4.1
- UniProt
- P17424
- Ligands
- FEO
- Pockets
- 1 · best druggability 0.33
Structure
x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein (ribonucleoside-diphosphate reductase small chain) (EC 1.17.4.1) | protein | 286 | 77% helix, 0% strand | P17424 |
| B | Protein (ribonucleoside-diphosphate reductase small chain) (EC 1.17.4.1) | protein | 285 | 77% helix, 0% strand | P17424 |
Ligands and binding sites
- FEO · Mu-oxo-diiron · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 73 | 0.33 | 0.75 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 2196 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 2R2F · Ribonucleotide reductase R2F protein from salmonella typhimurium (oxidized) · the same entry in another collection · chain A against A, TM-score 1.00
- P17424 · AlphaFold monomer V2.0 prediction for ribonucleoside-diphosphate reductase 2 subunit beta… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17424
- Elsewhere: RCSB PDB 2R2F · PDBe 2R2F · UniProt P17424
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