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Crystal structure of human mitoneet reveals a novel [2FE-2S] cluster coordination

Analyse Crystal structure of human mitoneet reveals a novel [2FE-2S] cluster… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2R13
Type: protein
Length: 76 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Zinc finger cdgsh domain-containing protein 1
UniProt: Q9NZ45
Ligands: FES, CL
Pockets: 1 · best druggability 0.29

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Zinc finger cdgsh domain-containing protein 1	protein	76	18% helix, 12% strand	Q9NZ45

Ligands and binding sites

FES · Fe2/s2 (inorganic) cluster · ligand · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.29	0.74	13	empty

Compared structures

2R13 · Crystal structure of human mitoNEET reveals a novel [2Fe-2S] cluster coordination · the same entry in another collection · chain A against A, TM-score 1.00
Q9NZ45 · AlphaFold monomer V2.0 prediction for cdgsh iron-sulfur domain- containing protein 1… · a predicted model of the same protein · chain A against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NZ45
Elsewhere: RCSB PDB 2R13 · PDBe 2R13 · UniProt Q9NZ45

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