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Crystal structure of the cysteine 91 threonine mutant of zebrafish liver bile acid-binding protein complexed with cholic acid

Analyse Crystal structure of the cysteine 91 threonine mutant of zebrafish liver bile… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2QO5
Type: protein
Length: 129 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Liver-basic fatty acid binding protein
UniProt: Q9I8L5
Ligands: CHD
Pockets: 1 · best druggability 0.84

Structure

x-ray diffraction · 1 distinct chain · 10% helix, 57% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Liver-basic fatty acid binding protein	protein	129	10% helix, 57% strand	Q9I8L5

Ligands and binding sites

CHD · Cholic acid · ligand · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	732	0.84	0.87	47	CHD

Compared structures

2QO5 · Crystal structure of the cysteine 91 threonine mutant of zebrafish liver bile… · the same entry in another collection · chain A against A, TM-score 1.00
Q9I8L5 · AlphaFold monomer V2.0 prediction for fatty acid-binding protein 10-a, liver basic… · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9I8L5
Elsewhere: RCSB PDB 2QO5 · PDBe 2QO5 · UniProt Q9I8L5

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