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Meab, a bacterial homolog of mmaa, bound to GDP

Analyse Meab, a bacterial homolog of mmaa, bound to GDP in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2QM7
Type: protein
Length: 625 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: GTPASE/ATPASE
UniProt: Q8RPA0
Ligands: GDP, PO4
Pockets: 9 · best druggability 0.68

Structure

x-ray diffraction · 2 distinct chains · 56% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	GTPASE/ATPASE	protein	314	55% helix, 12% strand	Q8RPA0
B	GTPASE/ATPASE	protein	311	57% helix, 12% strand	Q8RPA0

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains A, B
PO4 · Phosphate ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	200	0.68	0.86	30	empty
2	426	0.64	0.77	57	empty
3	265	0.62	0.81	40	empty
4	233	0.55	0.78	30	empty
5	105	0.53	0.83	23	empty

Interfaces

1 interface between chains.

A–B · 2512 Å² buried · 24 hydrogen bonds · protein-protein

Compared structures

2QM7 · MeaB, A Bacterial Homolog of MMAA, Bound to GDP · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8RPA0
Elsewhere: RCSB PDB 2QM7 · PDBe 2QM7 · UniProt Q8RPA0

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