Research workbench
Crystal structure of cell division protein ftsz from mycobacterium tuberculosis in complex with citrate.
Analyse Crystal structure of cell division protein ftsz from mycobacterium tuberculosis… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2Q1X
- Type
- protein
- Length
- 585 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell division protein ftsz
- UniProt
- P64170
- Pockets
- 5 · best druggability 0.69
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cell division protein ftsz | protein | 298 | 46% helix, 25% strand | P64170 |
| B | Cell division protein ftsz | protein | 287 | 44% helix, 25% strand | P64170 |
Ligands and binding sites
- CIT · Citric acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 435 | 0.69 | 0.80 | 54 | empty |
| 2 | 259 | 0.58 | 0.79 | 32 | empty |
| 3 | 143 | 0.50 | 0.79 | 25 | empty |
| 4 | 144 | 0.47 | 0.77 | 33 | empty |
| 5 | 100 | 0.42 | 0.78 | 25 | CIT |
Interfaces
1 interface between chains.
- A–B · 1081 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 2Q1X · Crystal Structure of cell division protein FtsZ from Mycobacterium tuberculosis in… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P64170
- Elsewhere: RCSB PDB 2Q1X · PDBe 2Q1X · UniProt P64170
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