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The structure of AIF2GAMMA subunit from the archaeon sulfolobus solfataricus in the nucleotide-free form.

Analyse The structure of AIF2GAMMA subunit from the archaeon sulfolobus solfataricus in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2PLF
Type: protein
Length: 414 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Translation initiation factor 2 gamma subunit
UniProt: Q980A5
Pockets: 5 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Translation initiation factor 2 gamma subunit	protein	414	15% helix, 37% strand	Q980A5

Pockets

5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	271	0.71	0.85	42	empty
2	264	0.63	0.81	50	empty
3	157	0.60	0.83	28	empty
4	272	0.57	0.78	33	empty
5	56	0.27	0.74	13	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

2PLF · The structure of aIF2gamma subunit from the archaeon Sulfolobus solfataricus in the… · the same entry in another collection · chain A against A, TM-score 1.00
Q980A5 · AlphaFold monomer V2.0 prediction for translation initiation factor 2 subunit gamma… · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q980A5
Elsewhere: RCSB PDB 2PLF · PDBe 2PLF · UniProt Q980A5

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