Research workbench

Crystal structure of genomically encoded fosfomycin resistance protein, fosx, from listeria monocytogenes (hexagonal form)

Analyse Crystal structure of genomically encoded fosfomycin resistance protein, fosx… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2P7K
Type: protein
Length: 242 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glyoxalase family protein
UniProt: Q71YW5
Pockets: 3 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 20% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Glyoxalase family protein	protein	121	20% helix, 32% strand	Q71YW5

Ligands and binding sites

CIT · Citric acid · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	245	0.83	0.95	33	empty
2	148	0.51	0.79	24	CIT
3	163	0.50	0.78	23	CIT

Interfaces

1 interface between chains.

A–B · 1825 Å² buried · 26 hydrogen bonds · protein-protein

Compared structures

2P7K · Crystal structure of genomically encoded fosfomycin resistance protein, FosX, from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q71YW5
Elsewhere: RCSB PDB 2P7K · PDBe 2P7K · UniProt Q71YW5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.