Structural basis for a novel interaction between AIP4 and beta-pix

Structure

x-ray diffraction · 2 distinct chains · 4% helix, 41% strand (DSSP).

Ligands and binding sites

• SO4 · Sulfate ion · ion · chains A
• GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–T · 679 Ų buried · 13 hydrogen bonds · protein-protein

Compared structures

• 2P4R · Structural basis for a novel interaction between AIP4 and beta-PIX · the same entry in another collection · chain A against A, TM-score 1.00
• O55043 · AlphaFold monomer V2.0 prediction for rho guanine nucleotide exchange factor 7 (O55043) · a predicted model of the same protein · chain A against A, TM-score 0.97
• Q96J02 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase itchy homolog (Q96J02) · a predicted model of the same protein · chain T against A, TM-score 0.21

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt O55043
• Every structure of UniProt Q96J02
• Elsewhere: RCSB PDB 2P4R · PDBe 2P4R · UniProt O55043 · UniProt Q96J02