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The crystal structure of the 2ND PDZ domain of the human nherf-1 (SLC9A3R1)

Analyse The crystal structure of the 2ND PDZ domain of the human nherf-1 (SLC9A3R1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2OZF
Type: protein
Length: 92 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ezrin-radixin-moesin-binding phosphoprotein 50
UniProt: O14745
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 1 distinct chain · 16% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ezrin-radixin-moesin-binding phosphoprotein 50	protein	92	16% helix, 36% strand	O14745

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	59	0.31	0.75	11	empty

Compared structures

2OZF · The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1) · the same entry in another collection · chain A against A, TM-score 1.00
O14745 · AlphaFold monomer V2.0 prediction for NA(+)/H(+) exchange regulatory cofactor nhe-RF1… · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O14745
Elsewhere: RCSB PDB 2OZF · PDBe 2OZF · UniProt O14745

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