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Crystal structure of UNG2/DNA(TM)
Analyse Crystal structure of UNG2/DNA(TM) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2OYT
- Type
- protein + DNA
- Length
- 242 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uracil-DNA glycosylase; DNA STRAND1; DNA STRAND2
- EC
- 3.2.2.-
- UniProt
- P13051
- Pockets
- 2 · best druggability 0.49
Structure
x-ray diffraction · 3 distinct chains · 40% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uracil-DNA glycosylase (EC 3.2.2.-) | protein | 223 | 40% helix, 11% strand | P13051 |
| B | DNA STRAND1 | dna | 9 | — | — |
| C | DNA STRAND2 | dna | 10 | — | — |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 260 | 0.49 | 0.74 | 25 | empty |
| 2 | 57 | 0.26 | 0.73 | 12 | empty |
Interfaces
3 interfaces between chains.
- A–B · 616 Ų buried · 10 hydrogen bonds · protein-nucleic
- B–C · 391 Ų buried · 33 hydrogen bonds · nucleic-nucleic
- A–C · 196 Ų buried · 1 hydrogen bond · protein-nucleic
Modifications
Observed in the structure: 2 modified (nucleotide modification).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13051
- Elsewhere: RCSB PDB 2OYT · PDBe 2OYT · UniProt P13051
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