UniProt P13051
Uracil-DNA glycosylase (P13051)
Uracil-DNA glycosylase (UniProt P13051), EC 3.2.2.27: 42 experimental structures on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P13051
- Protein
- Uracil-DNA glycosylase
- EC
- 3.2.2.27
- Experimental structures
- 42
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 3 · 1 record with a druggable one
Structures
42 records of P13051 in the MolNFT archive: 42 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1AKZ | Human uracil-DNA glycosylase | x-ray diffraction | A | — | — |
| 1AKZ | Human uracil-DNA glycosylase | x-ray diffraction | A | — | — |
| 1DPU | Solution structure of the C-terminal domain of human RPA32 complexed with UNG2(73-88) | solution nmr | B | — | — |
| 1DPU | Solution structure of the C-terminal domain of human RPA32 complexed with UNG2(73-88) | solution nmr | B | — | — |
| 1EMH | Crystal structure of human uracil-DNA glycosylase bound to uncleaved substrate-containing DNA | x-ray diffraction | A | — | — |
| 1EMH | Crystal structure of human uracil-DNA glycosylase bound to uncleaved substrate-containing DNA | x-ray diffraction | A | — | — |
| 1EMJ | Uracil-DNA glycosylase bound to DNA containing a 4'-thio-2'DEOXYURIDINE analog product | x-ray diffraction | A | — | — |
| 1EMJ | Uracil-DNA glycosylase bound to DNA containing a 4'-thio- 2'DEOXYURIDINE analog product | x-ray diffraction | A | — | — |
| 1Q3F | Uracil DNA glycosylase bound to a cationic 1-aza-2'-deoxyribose-containing DNA | x-ray diffraction | A | — | — |
| 1Q3F | Uracil DNA glycosylase bound to a cationic 1-aza-2'-deoxyribose- containing DNA | x-ray diffraction | A | — | — |
| 1SSP | Wild-type uracil-DNA glycosylase bound to uracil-containing DNA | x-ray diffraction | E | — | — |
| 1SSP | Wild-type uracil-DNA glycosylase bound to uracil-containing DNA | x-ray diffraction | E | — | — |
| 1UGH | Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein… | x-ray diffraction | E | — | — |
| 1UGH | Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein… | x-ray diffraction | E | — | — |
| 1YUO | Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA… | x-ray diffraction | A | — | — |
| 1YUO | Optimisation of the surface electrostatics as a strategy for cold adaptation of uracil-DNA… | x-ray diffraction | A | — | — |
| 2HXM | Complex of UNG2 and a small Molecule synthetic Inhibitor | x-ray diffraction | A | — | — |
| 2HXM | Complex of UNG2 and a small molecule synthetic inhibitor | x-ray diffraction | A | — | — |
| 2OXM | Crystal structure of a UNG2/modified DNA complex that represent a stabilized short-lived… | x-ray diffraction | A | — | — |
| 2OXM | Crystal structure of a UNG2/MODIFIED DNA complex that represent a stabilized short-lived… | x-ray diffraction | A | — | — |
| 2OYT | Crystal Structure of UNG2/DNA(TM) | x-ray diffraction | A | — | — |
| 2OYT | Crystal structure of UNG2/DNA(TM) | x-ray diffraction | A | — | — |
| 2SSP | Leucine-272-alanine uracil-DNA glycosylase bound to abasic site-containing DNA | x-ray diffraction | E | — | — |
| 2SSP | Leucine-272-alanine uracil-DNA glycosylase bound to abasic site- containing DNA | x-ray diffraction | E | — | — |
| 3FCF | Complex of UNG2 and a fragment-based designed inhibitor | x-ray diffraction | A | — | — |
| 3FCF | Complex of UNG2 and a fragment-based designed inhibitor | x-ray diffraction | A | — | — |
| 3FCI | Complex of UNG2 and a fragment-based designed inhibitor | x-ray diffraction | A | — | — |
| 3FCI | Complex of UNG2 and a fragment-based designed inhibitor | x-ray diffraction | A | — | — |
| 3FCK | Complex of UNG2 and a fragment-based design inhibitor | x-ray diffraction | B | — | — |
| 3FCK | Complex of UNG2 and a fragment-based design inhibitor | x-ray diffraction | B | — | — |
| 3FCL | Complex of UNG2 and a fragment-based designed inhibitor | x-ray diffraction | A, B | — | — |
| 3FCL | Complex of UNG2 and a fragment-based designed inhibitor | x-ray diffraction | A, B | — | — |
| 3TKB | crystal structure of human uracil-DNA glycosylase D183G/K302R mutant | x-ray diffraction | A | — | — |
| 3TKB | Crystal structure of human uracil-DNA glycosylase D183G/K302R mutant | x-ray diffraction | A | — | — |
| 4SKN | A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA | x-ray diffraction | E | — | — |
| 4SKN | A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA | x-ray diffraction | E | — | — |
| 5AYR | The crystal structure of SAUGI/human UDG complex | x-ray diffraction | A, C | MG | 3 (best 0.76) |
| 5AYR | The crystal structure of SAUGI/HUMAN udg complex | x-ray diffraction | A, C | — | — |
| 5JK7 | The X-ray structure of the DDB1-DCAF1-vpr-UNG2 complex | x-ray diffraction | D, G | — | — |
| 6VBA | Structure of human uracil DNA glycosylase (udg) bound to aurintricarboxylic acid (ata) | x-ray diffraction | A | QU4 | — |
| 7V7C | Cryoem structure of DDB1-vprbp-vpr-UNG2(94-313) complex | electron microscopy | D, H | — | — |
| P13051 | AlphaFold monomer V2.0 prediction for uracil-DNA glycosylase (P13051) | — | — | — |
Ligands
Elsewhere
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