Research workbench
Complex of barrier-to-autointegration factor and lem-domain of emerin
Analyse Complex of barrier-to-autointegration factor and lem-domain of emerin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2ODG
- Type
- protein
- Length
- 225 residues
- Chains
- 3
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Barrier-to-autointegration factor; Emerin
- UniProt
- O75531, P50402
- Pockets
- 1 · best druggability 0.36
Structure
solution nmr · 2 distinct chains · 67% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Barrier-to-autointegration factor | protein | 89 | 65% helix, 2% strand | O75531 |
| C | Emerin | protein | 47 | 70% helix, 0% strand | P50402 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 108 | 0.36 | 0.74 | 16 | empty |
Interfaces
3 interfaces between chains.
- A–B · 733 Ų buried · 1 hydrogen bond · protein-protein
- A–C · 348 Ų buried · 1 hydrogen bond · protein-protein
- B–C · 231 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 2ODG · Complex of barrier-to-autointegration factor and LEM-domain of emerin · the same entry in another collection · chain A against A, TM-score 1.00
- O75531 · AlphaFold monomer V2.0 prediction for barrier-to-autointegration factor (O75531) · a predicted model of the same protein · chain A against A, TM-score 0.94
- P50402 · AlphaFold monomer V2.0 prediction for emerin (P50402) · a predicted model of the same protein · chain C against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75531
- Every structure of UniProt P50402
- Elsewhere: RCSB PDB 2ODG · PDBe 2ODG · UniProt O75531 · UniProt P50402
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