UniProt O75531
Barrier-to-autointegration factor (O75531)
Barrier-to-autointegration factor (UniProt O75531): 46 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O75531
- Protein
- Barrier-to-autointegration factor
- Experimental structures
- 46
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 11 · 2 records with a druggable one
Structures
47 records of O75531 in the MolNFT archive: 46 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CI4 | The crystal structure of human barrier-to-autointegration factor (baf) | x-ray diffraction | A, B | — | — |
| 1CI4 | The crystal structure of human barrier-to-autointegration factor (baf) | x-ray diffraction | A, B | — | — |
| 1QCK | Solution structure of human barrier-to-autointegration factor baf, NMR, regularized mean structure… | solution nmr | A, B | — | — |
| 1QCK | Solution structure of human barrier-to-autointegration factor baf, NMR, regularized mean structure… | solution nmr | A, B | — | — |
| 2BZF | Structural basis for DNA bridging by barrier-to-autointegration factor (BAF) | x-ray diffraction | A | — | — |
| 2BZF | Structural basis for DNA bridging by barrier-to- autointegration factor (baf) | x-ray diffraction | A | — | — |
| 2EZX | Solution structure of human barrier-to-autointegration factor baf, NMR, regularized mean structure | solution nmr | A, B | — | — |
| 2EZX | Solution structure of human barrier-to-autointegration factor baf, NMR, regularized mean structure | solution nmr | A, B | — | — |
| 2EZY | Solution structure of human barrier-to-autointegration factor baf, NMR, ensemble of 20 simulated… | solution nmr | A, B | — | — |
| 2EZY | Solution structure of human barrier-to-autointegration factor baf, NMR, ensemble of 20 simulated… | solution nmr | A, B | — | — |
| 2EZZ | Solution structure of human barrier-to-autointegration factor baf NMR, ensemble of 20 simulated… | solution nmr | A, B | — | — |
| 2EZZ | Solution structure of human barrier-to-autointegration factor baf NMR, ensemble of 20 simulated… | solution nmr | A, B | — | — |
| 2ODG | Complex of barrier-to-autointegration factor and LEM-domain of emerin | solution nmr | A, B | — | — |
| 2ODG | Complex of barrier-to-autointegration factor and lem-domain of emerin | solution nmr | A, B | — | — |
| 6GHD | Structural analysis of the ternary complex between lamin A/C, baf and emerin identifies an… | x-ray diffraction | D, E, A, C | SO4 | — |
| 6UNT | Barrier-to-autointegration factor soaked in dmso: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6URE | Barrier-to-autointegration factor Aqueous: 1 of 14 in MSCS set | x-ray diffraction | A, B | — | — |
| 6URE | Barrier-to-autointegration factor aqueous: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6URJ | Barrier-to-autointegration factor soaked in Acetone: 1 of 14 in MSCS set | x-ray diffraction | A, B | — | — |
| 6URJ | Barrier-to-autointegration factor soaked in acetone: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6URK | Barrier-to-autointegration factor soaked in Glycerol: 1 of 14 in MSCS set | x-ray diffraction | A, B | — | — |
| 6URK | Barrier-to-autointegration factor soaked in glycerol: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6URL | Barrier-to-autointegration factor soaked in isopropanol: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6URN | Barrier-to-autointegration factor t-butanol: 1 of 14 in MSCS set | x-ray diffraction | A, B | — | — |
| 6URN | Barrier-to-autointegration factor T-butanol: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6URR | Barrier-to-autointegration factor soaked in Dioxane: 1 of 14 in MSCS set | x-ray diffraction | A, B | — | — |
| 6URR | Barrier-to-autointegration factor soaked in dioxane: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6URZ | Barrier-to-autointegration factor soaked in methanol: 1 of 14 in MSCS set | x-ray diffraction | A, B | — | — |
| 6URZ | Barrier-to-autointegration factor soaked in methanol: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6US0 | Barrier-to-autointegration factor soaked in R,S,R-bisfuranol (RSR): 1 of 14 in MSCS set | x-ray diffraction | A, B | — | — |
| 6US0 | Barrier-to-autointegration factor soaked in R,S,R-bisfuranol (rsr): 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6US1 | Barrier-to-autointegration factor soaked in isobutanol: 1 of 14 in MSCS set | x-ray diffraction | A, B | — | — |
| 6US1 | Barrier-to-autointegration factor soaked in isobutanol: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6US7 | Barrier-to-autointegration factor soaked in TMAO: 1 of 14 in MSCS set | x-ray diffraction | A, B | — | — |
| 6US7 | Barrier-to-autointegration factor soaked in tmao: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6USB | Barrier-to-autointegration factor soaked in urea: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6USD | Barrier-to-autointegration factor soaked in ethanol: 1 of 14 in MSCS set | x-ray diffraction | A, B | — | — |
| 6USD | Barrier-to-autointegration factor soaked in ethanol: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 6USI | Barrier-to-autointegration factor soaked in 1,6-hexanediol: 1 of 14 in MSCS set | x-ray diffraction | A, B | — | — |
| 6USI | Barrier-to-autointegration factor soaked in 1,6-hexanediol: 1 of 14 in mscs set | x-ray diffraction | A, B | — | — |
| 7ABM | X-ray structure of phosphorylated Barrier-to-autointegration factor (BAF) | x-ray diffraction | A | CS | — |
| 7ABM | X-ray structure of phosphorylated barrier-to-autointegration factor (baf) | x-ray diffraction | A | CS | — |
| 7NDY | Di-phosphorylated Barrier-to-Autointegration Factor (BAF) in complex with LEM domain of Emerin | x-ray diffraction | A, B | — | 1 (best 0.31) |
| 7NDY | Di-phosphorylated barrier-to-autointegration factor (baf) in complex with lem domain of emerin | x-ray diffraction | A, B | — | — |
| 7Z21 | BAF A12T bound to the lamin A/C Ig-fold domain | x-ray diffraction | A, B, C, D | CL | 5 (best 0.76) |
| 7Z21 | Baf A12T bound to the lamin A/C ig-fold domain | x-ray diffraction | A, B, C, D | CL | 5 (best 0.76) |
| O75531 | AlphaFold monomer V2.0 prediction for barrier-to-autointegration factor (O75531) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6URK chain B against the predicted model O75531: TM-score 0.98, RMSD 0.46 Å
- 6URK chain B against the predicted model O75531: TM-score 0.98, RMSD 0.46 Å
- 6URR chain B against the predicted model O75531: TM-score 0.98, RMSD 0.47 Å
- 6URR chain B against the predicted model O75531: TM-score 0.98, RMSD 0.47 Å
- 6URL chain B against the predicted model O75531: TM-score 0.98, RMSD 0.47 Å
- 7Z21 chain C against the predicted model O75531: TM-score 0.98, RMSD 0.43 Å
- 7Z21 chain C against the predicted model O75531: TM-score 0.98, RMSD 0.43 Å
- 6URN chain B against the predicted model O75531: TM-score 0.98, RMSD 0.48 Å
- 6URN chain B against the predicted model O75531: TM-score 0.98, RMSD 0.48 Å
- 6USB chain B against the predicted model O75531: TM-score 0.98, RMSD 0.49 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.