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Structural and biochemical analysis of a prototypical ATPase from the type III secretion system of pathogenic bacteria

Analyse Structural and biochemical analysis of a prototypical ATPase from the type III… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2OBL
Type: protein
Length: 346 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Escn
UniProt: O52140
Ligands: CA
Pockets: 5 · best druggability 0.44

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Escn	protein	346	41% helix, 18% strand	O52140

Ligands and binding sites

CA · Calcium ion · metal · chains A
ACT · Acetate ion · additive · chains A
IMD · Imidazole · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	119	0.44	0.78	23	IMD
2	130	0.42	0.76	32	empty
3	78	0.36	0.76	17	empty
4	63	0.35	0.77	17	empty
5	50	0.27	0.74	15	empty

Compared structures

2OBL · Structural and biochemical analysis of a prototypical ATPase from the type III secretion… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O52140
Elsewhere: RCSB PDB 2OBL · PDBe 2OBL · UniProt O52140

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