Research workbench
Solution structure of the spindle assembly checkpoint protein human MAD2
Analyse Solution structure of the spindle assembly checkpoint protein human MAD2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1DUJ
- Type
- protein
- Length
- 187 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Spindle assembly checkpoint protein
- UniProt
- Q13257
- Pockets
- 3 · best druggability 0.63
Structure
solution nmr · 1 distinct chain · 29% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Spindle assembly checkpoint protein | protein | 187 | 29% helix, 29% strand | Q13257 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 348 | 0.63 | 0.79 | 50 | empty |
| 2 | 74 | 0.42 | 0.80 | 19 | empty |
| 3 | 89 | 0.35 | 0.74 | 15 | empty |
Compared structures
- 1DUJ · Solution structure of the spindle assembly checkpoint protein human MAD2 · the same entry in another collection · chain A against A, TM-score 1.00
- Q13257 · AlphaFold monomer V2.0 prediction for mitotic spindle assembly checkpoint protein MAD2A… · a predicted model of the same protein · chain A against A, TM-score 0.63
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13257
- Elsewhere: RCSB PDB 1DUJ · PDBe 1DUJ · UniProt Q13257
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