Research workbench
The structure of uncharacterized protein TM1266 from thermotoga maritima.
Analyse The structure of uncharacterized protein TM1266 from thermotoga maritima. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2NZC
- Type
- protein
- Length
- 323 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical protein
- UniProt
- Q9X0Z3
- Ligands
- PO4
- Pockets
- 4 · best druggability 0.77
Structure
x-ray diffraction · 3 distinct chains · 37% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | Hypothetical protein | protein | 80 | 39% helix, 45% strand | Q9X0Z3 |
| B | Hypothetical protein | protein | 81 | 37% helix, 44% strand | Q9X0Z3 |
| D | Hypothetical protein | protein | 82 | 37% helix, 44% strand | Q9X0Z3 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · chains A
- ACY · Acetic acid · additive · 4 copies · chains A, C, B, D
- GOL · Glycerol · additive · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 570 | 0.77 | 0.83 | 53 | PO4, ACY, GOL |
| 2 | 437 | 0.75 | 0.84 | 49 | ACY |
| 3 | 175 | 0.48 | 0.76 | 18 | empty |
| 4 | 156 | 0.45 | 0.75 | 16 | empty |
Interfaces
6 interfaces between chains.
- A–B · 1104 Ų buried · 10 hydrogen bonds · protein-protein
- C–D · 1061 Ų buried · 8 hydrogen bonds · protein-protein
- B–D · 441 Ų buried · 15 hydrogen bonds · protein-protein
- A–C · 400 Ų buried · 11 hydrogen bonds · protein-protein
- B–C · 86 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 2NZC · The structure of uncharacterized protein TM1266 from Thermotoga maritima. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X0Z3
- Elsewhere: RCSB PDB 2NZC · PDBe 2NZC · UniProt Q9X0Z3
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