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Structural model for the N-terminal domain of human CDC37

Analyse Structural model for the N-terminal domain of human CDC37 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2NCA
Type: protein
Length: 126 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: HSP90 co-chaperone CDC37
UniProt: Q16543
Pockets: 1 · best druggability 0.34

Structure

solution nmr · 1 distinct chain · 65% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	HSP90 co-chaperone CDC37	protein	126	65% helix, 0% strand	Q16543

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	76	0.34	0.75	15	empty

Compared structures

2NCA · Structural Model for the N-terminal Domain of Human Cdc37 · the same entry in another collection · chain A against A, TM-score 1.00
Q16543 · AlphaFold monomer V2.0 prediction for HSP90 co-chaperone CDC37 (Q16543) · a predicted model of the same protein · chain A against A, TM-score 0.47

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q16543
Elsewhere: RCSB PDB 2NCA · PDBe 2NCA · UniProt Q16543

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