Research workbench
Structure and 15N relaxation data of calmodulin bound to the endothelial nitric oxide synthase calmodulin binding domain peptide at physiological calcium concentration
Analyse Structure and 15N relaxation data of calmodulin bound to the endothelial nitric… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2N8J
- Type
- protein
- Length
- 170 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Calmodulin; Nitric oxide synthase, endothelial
- UniProt
- P62158, P29474
- Pockets
- 2 · best druggability 0.49
Structure
solution nmr · 2 distinct chains · 36% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Calmodulin | protein | 148 | 37% helix, 5% strand | P62158 |
| B | Nitric oxide synthase, endothelial | protein | 22 | 32% helix, 0% strand | P29474 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 156 | 0.49 | 0.78 | 30 | empty |
| 2 | 65 | 0.30 | 0.74 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1208 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 2N8J · Structure and 15N relaxation data of Calmodulin bound to the endothelial Nitric Oxide… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62158
- Every structure of UniProt P29474
- Elsewhere: RCSB PDB 2N8J · PDBe 2N8J · UniProt P62158 · UniProt P29474
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.