Research workbench
NMR structures of the ALPHA7 nachr transmembrane domain.
Analyse NMR structures of the ALPHA7 nachr transmembrane domain. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2MAW
- Type
- protein
- Length
- 134 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Neuronal acetylcholine receptor subunit alpha-7
- UniProt
- P36544
- Pockets
- 2 · best druggability 0.81
Structure
solution nmr · 1 distinct chain · 72% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neuronal acetylcholine receptor subunit alpha-7 | protein | 134 | 72% helix, 0% strand | P36544 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 581 | 0.81 | 0.86 | 63 | empty |
| 2 | 98 | 0.47 | 0.81 | 22 | empty |
Compared structures
- 2MAW · NMR structures of the alpha7 nAChR transmembrane domain. · the same entry in another collection · chain A against A, TM-score 1.00
- P36544 · AlphaFold monomer V2.0 prediction for neuronal acetylcholine receptor subunit alpha-7… · a predicted model of the same protein · chain A against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P36544
- Elsewhere: RCSB PDB 2MAW · PDBe 2MAW · UniProt P36544
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