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Independently verified structure of GP41-M-mat, a membrane associated mper trimer from HIV-1 GP41
Analyse Independently verified structure of GP41-M-mat, a membrane associated mper… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2M7W
- Type
- protein
- Length
- 177 residues
- Chains
- 3
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Envelope glycoprotein
- UniProt
- M1E1E4
- Pockets
- 2 · best druggability 0.71
Structure
solution nmr · 1 distinct chain · 53% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Envelope glycoprotein | protein | 59 | 53% helix, 14% strand | M1E1E4 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 102 | 0.71 | 0.93 | 23 | empty |
| 2 | 52 | 0.28 | 0.74 | 12 | empty |
Interfaces
3 interfaces between chains.
- B–C · 761 Ų buried · 6 hydrogen bonds · protein-protein
- A–C · 755 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 747 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 2M7W · Independently verified structure of gp41-M-MAT, a membrane associated MPER trimer from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt M1E1E4
- Elsewhere: RCSB PDB 2M7W · PDBe 2M7W · UniProt M1E1E4
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