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NMR solution structure of the C-terminus of the minichromosome maintenance protein mcm from sulfolobus solfataricus

Analyse NMR solution structure of the C-terminus of the minichromosome maintenance… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2M45
Type: protein
Length: 87 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Minichromosome maintenance protein mcm
EC: 3.6.4.12
UniProt: Q9UXG1
Pockets: 1 · best druggability 0.37

Structure

solution nmr · 1 distinct chain · 53% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Minichromosome maintenance protein mcm (EC 3.6.4.12)	protein	87	53% helix, 13% strand	Q9UXG1

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	102	0.37	0.74	13	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

2M45 · NMR solution structure of the C-terminus of the minichromosome maintenance protein MCM… · the same entry in another collection · chain A against A, TM-score 1.00
Q9UXG1 · AlphaFold monomer V2.0 prediction for minichromosome maintenance protein mcm (Q9UXG1) · a predicted model of the same protein · chain A against A, TM-score 0.74

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UXG1
Elsewhere: RCSB PDB 2M45 · PDBe 2M45 · UniProt Q9UXG1

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