Research workbench
Solution-state NMR structure of cataract-related human GAMMA(S)- crystallin point variant G18V
Analyse Solution-state NMR structure of cataract-related human GAMMA(S)- crystallin… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2M3U
- Type
- protein
- Length
- 178 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-crystallin S
- UniProt
- P22914
- Pockets
- 2 · best druggability 0.43
Structure
solution nmr · 1 distinct chain · 6% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Beta-crystallin S | protein | 178 | 6% helix, 26% strand | P22914 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 72 | 0.43 | 0.81 | 14 | empty |
| 2 | 74 | 0.36 | 0.77 | 16 | empty |
Compared structures
- 2M3U · Solution-state NMR structure of cataract-related human gamma(S)-crystallin point variant… · the same entry in another collection · chain A against A, TM-score 1.00
- P22914 · AlphaFold monomer V2.0 prediction for gamma-crystallin S (P22914) · a predicted model of the same protein · chain A against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22914
- Elsewhere: RCSB PDB 2M3U · PDBe 2M3U · UniProt P22914
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