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Solution-state NMR structure of wild-type human GAMMA(S)-crystallin

Analyse Solution-state NMR structure of wild-type human GAMMA(S)-crystallin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2M3T
Type: protein
Length: 178 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-crystallin S
UniProt: P22914
Pockets: 2 · best druggability 0.48

Structure

solution nmr · 1 distinct chain · 5% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-crystallin S	protein	178	5% helix, 33% strand	P22914

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	104	0.48	0.80	24	empty
2	73	0.39	0.79	16	empty

Compared structures

2M3T · Solution-state NMR structure of wild-type human gamma(S)-crystallin · the same entry in another collection · chain A against A, TM-score 1.00
P22914 · AlphaFold monomer V2.0 prediction for gamma-crystallin S (P22914) · a predicted model of the same protein · chain A against A, TM-score 0.92

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22914
Elsewhere: RCSB PDB 2M3T · PDBe 2M3T · UniProt P22914

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