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Calmodulin, I85L, F92E, H107I, L112R, A128T, M144R mutant

Analyse Calmodulin, I85L, F92E, H107I, L112R, A128T, M144R mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2M3S
Type: protein
Length: 151 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Calmodulin
UniProt: P62149
Ligands: CA
Pockets: 1 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 58% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Calmodulin	protein	151	58% helix, 3% strand	P62149

Ligands and binding sites

CA · Calcium ion · metal · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	125	0.41	0.75	23	empty

Compared structures

2M3S · Calmodulin, i85l, f92e, h107i, l112r, a128t, m144r mutant · the same entry in another collection · chain A against A, TM-score 1.00
P62149 · AlphaFold monomer V2.0 prediction for calmodulin (P62149) · a predicted model of the same protein · chain A against A, TM-score 0.55

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P62149
Elsewhere: RCSB PDB 2M3S · PDBe 2M3S · UniProt P62149

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