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NMR solution structure of eph receptor

Analyse NMR solution structure of eph receptor in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2LW8
Type: protein
Length: 183 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ephrin type-a receptor 4
UniProt: P54764
Pockets: 2 · best druggability 0.64

Structure

solution nmr · 1 distinct chain · 4% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ephrin type-a receptor 4	protein	183	4% helix, 30% strand	P54764

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	104	0.64	0.88	21	empty
2	138	0.49	0.78	24	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

2LW8 · NMR solution structure of Eph receptor · the same entry in another collection · chain A against A, TM-score 1.00
P54764 · AlphaFold monomer V2.0 prediction for ephrin type-a receptor 4 (P54764) · a predicted model of the same protein · chain A against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P54764
Elsewhere: RCSB PDB 2LW8 · PDBe 2LW8 · UniProt P54764

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