Research workbench
NMR structures of the transmembrane domains of the nachr A4 subunit
Analyse NMR structures of the transmembrane domains of the nachr A4 subunit in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2LLY
- Type
- protein
- Length
- 134 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Neuronal acetylcholine receptor subunit alpha-4
- UniProt
- P43681
- Pockets
- 2 · best druggability 0.74
Structure
solution nmr · 1 distinct chain · 67% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neuronal acetylcholine receptor subunit alpha-4 | protein | 134 | 67% helix, 0% strand | P43681 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 484 | 0.74 | 0.82 | 45 | empty |
| 2 | 70 | 0.31 | 0.74 | 14 | empty |
Compared structures
- 2LLY · NMR structures of the transmembrane domains of the nAChR a4 subunit · the same entry in another collection · chain A against A, TM-score 1.00
- P43681 · AlphaFold monomer V2.0 prediction for neuronal acetylcholine receptor subunit alpha-4… · a predicted model of the same protein · chain A against A, TM-score 0.60
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43681
- Elsewhere: RCSB PDB 2LLY · PDBe 2LLY · UniProt P43681
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