Research workbench

IF2-G2 GDP complex

Analyse IF2-G2 GDP complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2LKD
Type: protein
Length: 178 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Translation initiation factor if-2
UniProt: P04766
Ligands: GDP
Pockets: 1 · best druggability 0.47

Structure

solution nmr · 1 distinct chain · 24% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Translation initiation factor if-2	protein	178	24% helix, 15% strand	P04766

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	123	0.47	0.79	26	empty

Compared structures

2LKD · IF2-G2 GDP complex · the same entry in another collection · chain A against A, TM-score 1.00
P04766 · AlphaFold monomer V2.0 prediction for translation initiation factor if-2 (P04766) · a predicted model of the same protein · chain A against A, TM-score 0.74

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P04766
Elsewhere: RCSB PDB 2LKD · PDBe 2LKD · UniProt P04766

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