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Solution structure of the R5 domain of talin

Analyse Solution structure of the R5 domain of talin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2L7N
Type: protein
Length: 168 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Talin-1
UniProt: P26039
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 1 distinct chain · 73% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Talin-1	protein	168	73% helix, 1% strand	P26039

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	76	0.33	0.74	18	empty

Compared structures

2L7N · Solution Structure of the R5 Domain of Talin · the same entry in another collection · chain A against A, TM-score 1.00
P26039 · AlphaFold monomer V2.0 prediction for talin-1 (P26039) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P26039
Elsewhere: RCSB PDB 2L7N · PDBe 2L7N · UniProt P26039

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