Research workbench

Fat domain of focal adhesion kinase tethered to LD4 motif of paxillin via ggs linker

Analyse Fat domain of focal adhesion kinase tethered to LD4 motif of paxillin via ggs… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2L6H
Type: protein
Length: 154 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Focal adhesion kinase 1, linker, paxillin
EC: 2.7.10.2
UniProt: Q00944, P49024
Pockets: 1 · best druggability 0.55

Structure

solution nmr · 1 distinct chain · 80% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Focal adhesion kinase 1, linker, paxillin (EC 2.7.10.2)	protein	154	80% helix, 0% strand	Q00944, P49024

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	75	0.55	0.86	17	empty

Compared structures

2L6H · Fat domain of focal adhesion kinase tethered to LD4 motif of paxillin via GGS linker · the same entry in another collection · chain A against A, TM-score 1.00
Q00944 · AlphaFold monomer V2.0 prediction for focal adhesion kinase 1 (Q00944) · a predicted model of the same protein · chain A against A, TM-score 0.68
P49024 · AlphaFold monomer V2.0 prediction for paxillin (P49024) · a predicted model of the same protein · chain A against A, TM-score 0.28

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q00944
Every structure of UniProt P49024
Elsewhere: RCSB PDB 2L6H · PDBe 2L6H · UniProt Q00944 · UniProt P49024

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.