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Solution structure of a bacterial cyclic nucleotide-activated K+ channel binding domain in the unliganded state

Analyse Solution structure of a bacterial cyclic nucleotide-activated K+ channel… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2KXL
Type: protein
Length: 142 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cyclic nucleotide-gated potassium channel MLL3241
UniProt: Q98GN8
Pockets: 1 · best druggability 0.44

Structure

solution nmr · 1 distinct chain · 37% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cyclic nucleotide-gated potassium channel MLL3241	protein	142	37% helix, 23% strand	Q98GN8

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	117	0.44	0.77	18	empty

Compared structures

2KXL · Solution structure of a bacterial cyclic nucleotide-activated K+ channel binding domain… · the same entry in another collection · chain A against A, TM-score 1.00
Q98GN8 · AlphaFold monomer V2.0 prediction for cyclic nucleotide-gated potassium channel MLL3241… · a predicted model of the same protein · chain A against A, TM-score 0.71

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q98GN8
Elsewhere: RCSB PDB 2KXL · PDBe 2KXL · UniProt Q98GN8

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