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Solution structure of NUSE:NUSG-ctd complex

Analyse Solution structure of NUSE:NUSG-ctd complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2KVQ
Type: protein
Length: 139 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nuse; Transcription antitermination protein nusg
UniProt: P0A7R5, P0AFG0
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 2 distinct chains · 18% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
E	Nuse	protein	80	31% helix, 43% strand	P0A7R5
G	Transcription antitermination protein nusg	protein	59	0% helix, 54% strand	P0AFG0

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	80	0.33	0.75	20	empty

Interfaces

1 interface between chains.

E–G · 556 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

2KVQ · Solution structure of NusE:NusG-CTD complex · the same entry in another collection · chain E against E, TM-score 1.00
P0AFG0 · AlphaFold monomer V2.0 prediction for transcription TERMINATION/ANTITERMINATION protein… · a predicted model of the same protein · chain G against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A7R5
Every structure of UniProt P0AFG0
Elsewhere: RCSB PDB 2KVQ · PDBe 2KVQ · UniProt P0A7R5 · UniProt P0AFG0

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